… To address the effect of weak TLR4 stimulation on virulence, we modified Y. … In summary,
a considerable deficit in response to LPS from Y. pestis grown at 37 C was common to cells …

… of rough LPS is essential for Pla activity and virulence in Y. … inflammatory response and
establish fatal infection (41). … genes to coordinate virulence factor expression within global gene …

… pestis uses a variety of mechanisms to evade or overcome … pestis immediately begins to
produce tetra-acylated LPS, … pestis virulence factors that dampen cellular responses and …

… pestis displays a quite unique set of virulence factors that allow successful infection of fleas
and subversion of immune responses in … a strong lipopolysaccharide response overcame Y. …

… it is a very important virulence factor for pneumonic plague [12]… pestis synthesizes different
forms of LPS depending on host… pestis overcomes the mucosal barriers, it is phagocytosed by …

… This work aims at unraveling the impact of particular LPS components on Y. pestis virulence,
… pestis pathogenicity factors responsible for systemic spread of bacteria in the host organism …

… We feel that they may have observed such strong adhesion … induce a less dramatic immune
response than wild-type Y. … in lipopolysaccharide-mediated immune stimulation (42, 51). …

… lipopolysaccharide (LPS) as one of the pathogenicity factors of … pestis LPS may play a crucial
role in overcoming the defence … a good illustration of the fact that the active (endotoxic) LPS …

… virulence outside the bacteria, and it has been proposed that LcrV acts directly to compromise
innate host immune responses… , an effect that was overcome by overexpressing lcrVin trans…

… immune response (36). In addition, a lack of O antigen and full … pOmpX-transformed colonies
with strong autoaggregation … pestis ompX gene is a novel essential virulence factor in a …